Credit course for supervised participation in faculty research project. Details at https://www.artsci.utoronto.ca/current/academics/research-opportunities/research-opportunities-program. Not eligible for CR/NCR option.

This course guides each student through their own individual research project, embedded in an interactive group learning process, to offer an applied introduction to research methods for peace, conflict and justice studies. Students work through the research in the field of peace, conflict and justice studies, such as: identifying a research question, learning how to write a critical literature review, developing a rigorous research design, and applying quantitative, qualitative, or mixed methods to answering research inquires. The final deliverable is a draft of a research proposal or an empirical research-based paper. This course is a requirement for PCJ Specialists and open to PCJ Majors with approval from the Director.

Topics vary annually. The objective of the course is to explore emerging issues in Peace and Conflict Studies. The focus of the course will be on a specific topic, rather than a broad survey of the field.

This course explores selected issues in the field of Peace, Conflict and Justice. Topics may vary from year to year. Through a suite of recent readings, students will strive to critically examine implications and challenges of, and solutions to the issues being studied. Please visit the Trudeau Centre for Peace, Conflict and Justice website for current offering information.

This course guides each student through their own individual research project, embedded in an interactive group learning process, in order to offer an applied introduction to research methods for peace, conflict and justice studies. Students work through the full research process, including: identifying a research question, learning how to conduct effective literature reviews, developing a rigorous research design, and applying quantitative and qualitative methods to answering questions. Rather than conducting research independently or studying research methods in isolation, the course combines the two: students learn collectively about the different steps in the research process while simultaneously applying those steps to their own research project. This is then complemented by presenting that research and discussing different research projects in class, so as to receive continuous feedback and be exposed to a variety of research methods and approaches.

This course is designed to provide students with the opportunity to explore topics not covered in the curriculum, or to develop a more detailed focus on topics covered. Approval of the program director is required. The student must obtain written agreement of the instructor who will supervise the independent study, submit the proposal to and obtain approval from the director and program administrator, who will then add the student to the course. Not eligible for CR/NCR option.

Applications are due two weeks before course enrolment deadlines.

This course introduces students to the processes and strategies for discovering new drugs with a special focus on current and emerging approaches for the rational design of drugs that are both effective and safe.

Lectures introduce students to prescribed and illicit drugs that affect the brain. Lectures cover drug pharmacology and explain how drugs alter mood, perception, cognition, and arousal by affecting different aspects of brain function. The societal impact of these prescribed and illicit drugs is also discussed.

Note: This course is not intended for upper-year students in Life Sciences. Upper-year Life Science students interested in this content should look into PCL475H1 and/or PCL476H1 as the more appropriate choice.

A general introduction to the principles of pharmacology and pharmacokinetics. Topics include chemical (drug) absorption, distribution, biotransformation, elimination; the calculation of dosages and pharmacokinetic parameters, variability in drug response, adverse drug reactions and special interest topics.

There is a critical need for a breadth of understanding regarding its mechanism of action, pharmacological effects and its potential benefits and harms (short- and long-term). Students will gain a breadth of understanding in cannabis-related topics including pharmacology and toxicology, its role in mental health and addictions, medical use, drug policy and new drug development that stems from increased access to cannabis constituents. They will learn to differentiate myths and anecdotes from evidence-based knowledge. Going forward it is imperative that students spanning basic sciences through business, arts and engineering have a comprehensive understanding of these topics. PCL218H1 will give students for a variety of academic backgrounds a basic understanding of the health implications of cannabis which have broad implications for both our professional and personal lives.

A formal opportunity to gain hands-on experience and develop their skills within a research laboratory setting. Students will have a chance to become familiar and efficient at good lab practices, develop critical thinking and evaluation skills while applying their knowledge and developing trouble shooting skills to practical research questions. Students are required to participate in active research for the equivalent of a minimum of 60 hours of laboratory time. This course is Pass/Fail. Not eligible for CR/NCR option. NOTE: students are required to secure their own supervisor for the course.

Permission of Faculty Supervisor and Department required.

Additional student information resources and enrollment form for the course can be found on the Pharmacology & Toxicology website here: https://pharmtox.utoronto.ca/undergraduate-courses

Following experience from PCL297H1, this follow up course provides students an opportunity to expand their hands-on experience and skill set within a research laboratory setting. This course is only open to students who have completed PCL297H1 and wish to continue their research opportunity with the same supervisor. Students will continue to develop good lab practices, critical thinking and evaluation skills while applying their knowledge and trouble shooting skills to practical research questions. Students are required to participate in active research for the equivalent of a minimum of 60 hours of laboratory time. Not eligible for CR/NCR option. NOTE: students are required to secure their own supervisor for the course.

Permission of Faculty Supervisor and Department required.

Additional student information resources and enrollment form for the course can be found on the Pharmacology & Toxicology website here: https://pharmtox.utoronto.ca/undergraduate-courses

Credit course for supervised participation in faculty research project. Details at https://www.artsci.utoronto.ca/current/academics/research-opportunities/research-opportunities-program. Not eligible for CR/NCR option.

Topics include biological action of drugs on membranes, enzymes, receptors, neural and hormonal systems, transmission and modulation.

Lecturers use their own research to demonstrate how they approach a biological question. The lectures emphasize why one approach is chosen over other possible approaches, and explain the strengths and limitations of techniques. Following the one-hour lecture there is an interactive discussion of the experimental approach covered in the lecture.

Toxicological problems encountered in animals and humans; biochemical mechanisms and clinical factors of toxicological significance; models of drug-related diseases.

This course will provide a learning experience that simulates the process, techniques, analysis and evaluation methods used for early-stage in vitro drug development. Modules will build on the student’s fundamental knowledge and will simulate and illustrate the thought processes and techniques that are used during new drug development in academic research institutes, clinical research organizations and pharmaceutical and biotechnology companies worldwide. Modules include target screening, cytotoxicity assays, transcriptional activation testing and metabolizing enzyme identification experiments. This experience will allow students to leverage their learned knowledge to improve their employability in this area, while honing their critical thinking and analytical skills. (Lab Materials Fee: $25)

This course will provide a learning experience that parallels and simulates the process, protocols, methods and evaluation tools used for later-stage in vivo drug development. Modules will build on the student’s fundamental knowledge and simulate the thought processes and techniques used during drug development in research institutes, clinical research organizations and pharmaceutical and biotechnology companies worldwide. Modules will include pharmacokinetic and pharmacodynamic analyses and pharmacogenetic screening approaches in model systems and humans. This experience will allow students to leverage their learned skills and knowledge to improve their comprehension and employability in this area, while honing critical thinking and analytical skills. (Lab Materials Fee: $25)

This course includes lectures focused on experimental design and the analysis of pharmacological and toxicological data. Topics include: principles of experimental design, data analysis and statistical tests appropriate for each type, use of computing statistical packages, analysis of dose-response and time-response curves and analysis of receptor binding assays. Practical applications and problem sets will be taken up in class and in tutorials. Not offered every year.

An introduction to Toxicology and an examination of biochemical principles and the molecular mechanisms that underlie toxicity of drugs and foreign agents. This course explores the sequence of molecular events that leads to cell function impairment and factors that determine and affect toxicity.

This course will expand on both classical and cutting edge pharmacological strategies proposed to mitigate the consequences of altered signal transduction in cancer. Students will have the opportunity to develop knowledge on these molecular events and how they can be targeted to improve clinical outcomes. Students will integrate lecture material with assigned readings and assignments.

This service learning course explores issues surrounding the effects that pharmaceuticals and chemicals have in society. Specifically, it integrates pharmacology and toxicology with social, health and political issues as they relate to drug abuse and addiction. Students are required to interact and work with community partners during the semester (approx. 20hrs). Classroom discussions will integrate community experiences with lecture material. Not eligible for CR/NCR option.

An independent research project in a pharmacology and/or toxicology laboratory in an approved partner university. This international research experience will be supervised by a faculty member at the partner institution and will allow students to develop critical thinking and evaluation skills while applying their knowledge and trouble shooting skills to practical research questions. Information regarding eligibility, application process and upcoming information session dates can be found on the Department of Pharmacology and Toxicology website here: PCL397Y0 Website. Not eligible for CR/NCR option. Contact undergrad.pharmtox@utoronto.ca for more information.

An independent research project in a pharmacology and/or toxicology research laboratory for inbound exchange students coming to the University of Toronto from an approved partner university. This research experience will be supervised by a faculty member and will allow students to develop critical thinking, communication and evaluation skills while applying their knowledge and trouble shooting skills within leading edge research questions. Information regarding eligibility, application process and upcoming information session dates can be found on the Department of Pharmacology and Toxicology website here: PCL397Y1 Website. Not eligible for CR/NCR option. Contact undergrad.pharmtox@utoronto.ca or the Centre for International Experience https://internationalexperience.utoronto.ca/ for more information.

Credit course for supervised participation in faculty research project. Details at https://www.artsci.utoronto.ca/current/academics/research-opportunities/research-opportunities-program. Not eligible for CR/NCR option.

This course provides the basic principles of drug development, with a primary focus on the application of fundamental principles of pharmacology and toxicology to the design of preclinical assays and early phase clinical trials. Students in the course will have the opportunity to engage in experiential learning in drug development projects for rare diseases.

A culmination of pharmacological principles discussing concepts of drug properties and their interactions within the body. The mechanism of action, pharmacological properties including clinical use and adverse effects of drugs acting on the autonomic nervous systems, cardiovascular, renal, respiratory, gastrointestinal and endocrine systems will be examined. Critical evaluation of primary literature and examination of clinical problem-based case studies will be integrated with lecture material through small group sessions.

A culmination of pharmacological principles discussing concepts of drug properties and their interactions within the body. The mechanism of action, pharmacological properties including clinical use and adverse effects of drugs acting on the central nervous systems and immunological system; antimicrobial and cancer chemotherapeutic agents as well as the potential therapeutic use of endogenous/herbal compounds will be examined. Critical evaluation of primary literature and examination of clinical problem-based case studies will be integrated with lecture material through small group sessions.

This course affords students an opportunity for hands-on research experience in a laboratory or applied pharmacology setting. Students will work under the supervision of a faculty member and will submit a final written report and oral presentation. Enrollment is limited to students in ASSPE2340/ASSPE2082 programs and requires permission from the Department of Pharmacology and Toxicology. It is the student’s responsibility to secure a placement with an approved supervisor before the course begins (a list of potential supervisors will be provided by the Department of Pharmacology and Toxicology). Students will be registered in the course once their ballot form (obtained from the Department) is signed by an approved supervisor and approved by the Department of Pharmacology and Toxicology. Eligible students will be contacted by the Department during the Winter term, occurring prior to their final year of study (i.e. 3rd year of study for most), with details and instructions to apply. Students are expected to spend approximately 200 hours towards this project but this will be project/supervisor dependent. Not eligible for CR/NCR option.

This course affords students an opportunity for hands-on research experience in a laboratory or applied toxicology setting. Students will work under the supervision of a staff member and will submit a final written report and oral presentation. Enrollment is limited to students in ASSPE2340/ASSPE2573/ASSPE0605 programs and requires permission from the Department of Pharmacology and Toxicology. It is the student’s responsibility to secure a placement with an approved supervisor before the course begins (a list of potential supervisors will be provided by the Department of Pharmacology and Toxicology). Students will be registered in the course once their ballot form (obtained from the Department) is signed by an approved supervisor and approved by the Department of Pharmacology and Toxicology. Eligible students will be contacted by the Department during the Winter term, occurring prior to their final year of study (i.e. 3rd year of study for most), with details and instructions to apply. Students are expected to spend approximately 200 hours towards this project but this will be project/supervisor dependent. Not eligible for CR/NCR option.