This course is an introduction to computational methods and internet resources in modern biochemistry and molecular biology. The main topics include: sequence and genome databases, sequence alignment and homology search, use and interpretation of molecular structure, and phylogenetic analysis. Assignments focus on hands-on competence building with web-based bioinformatics tools and databases, downloadable software including a molecular viewer and a multiple sequence alignment editor, and the statistics workbench and programming language “R”. For syllabus details see: http://steipe.biochemistry.utoronto.ca/abc
Note: BCB420H1 extends this syllabus to computational topics of systems biology.